Discovery of an antidote to the poison of Amanita phalloides

Although mushroom poisoning is not a major public health problem, it is understood, each year in France there are a few dozen serious cases and a handful of deaths (between 0 and 5). It is a family of poisons in particular, amanitins, which are almost always responsible, especially because they resist cooking and desiccation.

"There are half a dozen fungi that produce these toxins, including several amanites, of course," says Francis Martin, INRAE Emeritus Research Director at the Tree-Microorganisms Interactions laboratory, who recently worked on the genetic origins of these toxins (Luo et al. PNAS, 2022). "Amanita phalloides is one of the main sources of poisoning," continues the specialist. It is usually confused with wood agaric, modest moth, slimy volvary, green russula or amanita citrine. A young virous amanita can hide...

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