That afternoon, on the ninth floor of one of the buildings of the Saint-Antoine Hospital in Paris, Sandrine Delage was busy filtering a funny brown liquid on her laboratory bench. "After mixing them with a freezing product, the stool is filtered twice to remove the residue. Then we transfer this mixture into capsules or syringes, "explains the young pharmacy preparer, covered from head to toe with protective equipment. A very serious matter. Because in this "microbiota transplant preparation unit", drugs based on human excrement are manufactured, particularly effective in treating a serious disease: multi-recurrent Clostridioides difficile infection (pronounced "difficult").
Sandrine Delage, a pharmacy preparer, filters a donor's stool to prepare the drug. Everything is done under an extraction hood to work in sterile conditions. Cécile Thibert
This bacterium, very present in our environment but also in the intestines of some people, can cause great damage. "As long as our gut microbiota (formerly called 'gut flora'...
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