One of the very first studies on vaccination with synthetic messenger RNA was published by a French team in 1993. Its authors, Frédéric Martinon and Pierre Meulien, report in the
European Journal of Immunology that
they succeeded in inducing, with Synthetic mRNA coated in lipid spheres, an immune response against the influenza virus in mice.
But the process, which seems difficult to reproduce, was not patented at the time.
Read also:
RNA, at the dawn of a new medicine
“Until recently, the scientific and medical community did not believe in the potential of this technology,”
observes Steve Pascolo, a French immunologist who was one of the first to focus on vaccine RNA from 1998.
“Unlike to prejudices, the molecule is very resistant in a test tube (it can be frozen or heated to 90 degrees), but fragile in the body where it is quickly destroyed, which guarantees its safety, ”he
explains.
"Extraordinary progress"
Despite the skepticism of their peers, a handful of teams
This article is for subscribers only.
You have 67% left to discover.
Subscribe: 1 € the first month
Can be canceled at any time
I ENJOY IT
Already subscribed?
Log in