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The microbiota, antidepressant of the future?

2023-01-08T15:48:55.481Z


DECRYPTION - There are links between chronic diseases and the intestinal microbiota. Mental illnesses also originate… in the digestive tract! When our microbiota is disturbed, families of undesirable bacteria colonize the intestine and produce inflammatory molecules. “Under their action, the digestive wall becomes porous: proteins that should not come out of it join the bloodstream and cause an immuno-inflammatory cascade that ends up reaching the brain ,” explains Dr. Ryad Tamouz


Mental illnesses also originate… in the digestive tract!

When our microbiota is disturbed, families of undesirable bacteria colonize the intestine and produce inflammatory molecules.

“Under their action, the digestive wall becomes porous: proteins that should not come out of it join the bloodstream and cause an immuno-inflammatory cascade that ends up reaching the brain

,” explains Dr. Ryad Tamouza, researcher and immunologist at the Henri-Mondor hospital (Créteil).

In the case of depression, 20% to 30% of patients are resistant to antidepressants and the hypothesis is that dysbiosis could explain all or part of these resistant depressions.

Hence the idea of ​​restoring the beneficial relationship between humans and the 50,000 billion bacteria that inhabit their intestines.

This is the Promood project, carried out within the FondaMental foundation with the start-up Gynov and researcher Joël Doré at the National Research Institute for…

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Source: lefigaro

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