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Key finding from Harvard to combat aging

2023-04-24T23:48:21.303Z


Scientists discovered how to reverse the effects of the passage of time, and it could be useful in humans.


How do I slow down aging?

The question that has been rumbling in the heads of scientists around the world for a long time now adds a new chapter after a key finding for the health of scientists from

Harvard University

It is known that

healthy eating, vitamins and exercises

undoubtedly help the skin and look younger.

But not everything has to do with an aesthetic issue, but it goes further.


Could Harvard reverse aging?

After a series of experiments, scientists

specializing in genetics

at Harvard University in the United States managed to reverse aging.

One of the results of the study was that aged and blind mice managed to regain their sight and developed younger brains.

The researchers were able

to double the life span of old mice

.

It is a work that took 13 years of development and was published a few months ago in

Cell magazine.

"We believe ours is the first study to show

epigenetic change

as the main driver of aging in mammals," said David Sinclair, lead author of the paper and professor of genetics at the Blavatnik Institute at Harvard Medical School and co-director. from the Paul F. Institute Glenn Center for Research in the Biology of Aging.

The study demonstrates that degradation in

the way DNA is organized and regulated

, known as epigenetics, can cause aging in an organism, independent of changes in the genetic code itself.

The Harvard Study

As they explain, the

observation and modification of the genome of laboratory rodents

, scientists caused aging and subsequent rejuvenation in rodents beyond changes in the genetic code.

David Sinclair, lead author of the paper on aging and professor of genetics at the Blavatnik Institute at Harvard Medical School.

The first step was to conduct studies in

non-human primates

.

“We hope that these results will be seen as a turning point in our ability to control aging.

This is the first study to show that we can have

precise control of the biological age of a complex animal

;

propel it forward and backward at will," Sinclair confirmed.

And he gave a practical example: "It's like restarting a computer that doesn't work correctly."

It was then that the questions arose.

And especially a key one:

Is it possible to bring this same process to humans?

In the event of an affirmative answer, it would be

one of the greatest steps in science

in terms of fighting against the natural evolution of people and would improve the quality of life 100%.

Is it possible to carry this same process from mice to humans?

Photo Shutterstock.


Cause of aging

Experiments show that changes in DNA

are not the only or the main cause of aging.

In fact, the finding attempts to make it clear that chemical and structural changes in chromatin drive the

senescence process without altering the genetic code itself

, the publication expands.

"Somehow, the cells know that the body can be reset, and they keep the knowledge about which genes were active when they were young," Sinclair said.

Reverse the effects of the passage of time, something that reveals science.

And he put on the table the example of some animals:

"When you cut the limb of an amphibian, it grows back.

The tail of a fish will grow back, the finger of a mouse will grow back."

look also

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Source: clarin

All news articles on 2023-04-24

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